2021 Annual Global Meeting: Virtual-Master Session: Uterine Cancer

Video Transcription

Video Summary

In this master session on uterine cancer, chaired by Dr. Domenica Lorusso, Dr. Xavier-Matthias Gouillou, and Dr. Brian Slomowitz, various experts discussed the state of the art and new perspectives in the treatment of uterine cancer. The session included three panel discussions on different topics.<br /><br />The first panel focused on the new molecular classification of endometrial cancer, presented by Dr. Gouillou. The importance of molecular classification in guiding treatment decisions was highlighted, allowing for the identification of different molecular subtypes with varied prognoses and treatment implications. The challenges and limitations of the classification were also discussed.<br /><br />The second panel discussed the adjuvant treatment of endometrial cancer, with Dr. Lorusso presenting on this topic. Current guidelines based on clinical and molecular characteristics were discussed, as well as different treatment options including radiation therapy, chemotherapy, and brachytherapy. Ongoing research, such as the use of immunotherapy and PARP inhibitors, was also mentioned.<br /><br />The video summarized various trials and treatment options for patients with endometrial cancer. It highlighted the potential role of checkpoint inhibitors in adjuvant treatment and ongoing trials exploring the best treatment based on molecular profiling. Experts from Europe and the US emphasized the need for further evidence in guiding adjuvant treatment based on molecular classification. They also discussed the potential of immunotherapy in metastatic or recurrent endometrial cancer, particularly in patients with specific genetic characteristics.<br /><br />Overall, the master session provided valuable insights into the importance of molecular classification and personalized treatment approaches for uterine cancer. The video recognized the need for international collaboration and ongoing research to improve treatment options for patients with this type of cancer.

Keywords

uterine cancer

molecular classification

endometrial cancer

treatment decisions

molecular subtypes

adjuvant treatment

radiation therapy

chemotherapy

brachytherapy

immunotherapy

PARP inhibitors

trials

checkpoint inhibitors

metastatic endometrial cancer

recurrent endometrial cancer