Didactics-Adjuvant Radiotherapy for Endometrial Cancer

Video Transcription

Video Summary

In this video, the speaker discusses the studies and recommendations for adjuvant radiotherapy for endometrial cancer. The speaker explains that the use of radiotherapy shifted from pre-operative to post-operative in the 1970s due to concerns of over-treatment. Several studies compared pelvic radiotherapy to no radiotherapy or vaginal brachytherapy. These studies found no difference in overall survival but a reduction in local recurrence and an increase in toxicity with radiotherapy. The speaker emphasizes the importance of identifying high-risk features and tailoring adjuvant treatment accordingly. The use of intensity modulated radiotherapy can reduce toxicity compared to conventional radiotherapy. Additional studies have clarified the role of chemotherapy in certain risk groups. The speaker also mentions the inclusion of molecular classification in guiding treatment decisions. The video ends with a summary of the current guidelines for different risk groups in endometrial cancer.

Asset Subtitle

Alexandra Taylor
July 2022

Keywords

adjuvant radiotherapy

endometrial cancer

toxicity

chemotherapy

current guidelines