Didactics-Management of Gestational Trophoblastic Disease

Video Transcription

Video Summary

The video transcript features a doctor from the Philippines discussing trophoblastic disease, specifically hydatidiform mole and choriocarcinoma. The doctor explains that trophoblastic disease is characterized by abnormal proliferation of the trophoblast. There are different forms of the disease, ranging from benign to malignant. The doctor notes that in the Philippines, they see a high number of cases, with up to two hydatidiform moles and four choriocarcinoma cases in a month. Diagnostic methods include ultrasound and beta-HCG testing. Treatment involves evacuating the molar product and monitoring HCG levels. The risk factors for post-molar gestational trophoblastic neoplasia are discussed. Choriocarcinoma is treated with chemotherapy, with methotrexate or actinomycin B used for stage 1 disease and combination or intensive chemotherapy for higher stages. Surgery and irradiation may be used as adjunctive treatment. Monitoring HCG levels is important in assessing treatment response. The doctor also mentions challenges during the COVID-19 pandemic and the need to prioritize patient safety.

Asset Subtitle

Maria Stephanie Fay S. Cagayan
August 2020

Keywords

trophoblastic disease

hydatidiform mole

choriocarcinoma

diagnostic methods

treatment