Didactics-Radical Hysterctomy for Cervical Cancer

Video Transcription

Video Summary

In this video, Dr. Linus Chuang discusses the different factors to consider when performing a radical hysterectomy for cervical cancer patients. He emphasizes that the right candidate for the surgery is a patient with stage 1A2 to 1B2 cervical cancer, specifically squamous adeno or small cell neuroendocrine tumors, who has undergone concurrent chemoradiation therapy and still has a small central disease. Dr. Chuang mentions that obese patients may be more challenging to operate on, but neoadjuvant chemotherapy could be considered as an alternative to surgery for these patients. He also discusses the outcomes of a study comparing minimally invasive radical hysterectomy to open radical hysterectomy, highlighting that minimally invasive approaches were associated with higher death rates and worse overall survival. Dr. Chuang suggests that an abdominal radical hysterectomy is currently the preferred surgical approach. He touches on the importance of considering different risk factors, such as lymphovascular space invasion or positive lymph nodes, when deciding on additional therapies after surgery. He also discusses the challenges faced in low-resource settings where radiation machines are scarce, and refers to studies that have explored the use of neoadjuvant chemotherapy followed by radical surgery as an alternative treatment option. Dr. Chuang concludes by recommending involvement in cooperative group research studies and highlights the importance of routine follow-up for patients after cervical cancer treatment.

Asset Subtitle

Linus Chuang
April 2021

Keywords

radical hysterectomy

cervical cancer

chemoradiation therapy

neoadjuvant chemotherapy

minimally invasive

abdominal radical hysterectomy