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Catalog
Didactics
Serous Tumours of the Ovary
Serous Tumours of the Ovary
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Video Transcription
Video Summary
In this video, the speaker discusses various types of ovarian tumors, focusing on serious tumors. Serious tumors of the ovary are classified as benign, borderline, or malignant, with the most common type being serious cystadenoma. The speaker provides details on the different histotypes and characteristics of serious tumors, including serious borderline tumors, which are non-invasive, low-grade proliferative tumors that have greater epithelial proliferation and cytological atypia compared to benign serious tumors. The speaker explains the gross features and histological characteristics of serious tumors, including the presence of papillary excrescences and cellular atypia. They also highlight the importance of evaluating the presence of stromal invasion in distinguishing between benign tumors, borderline tumors, and low-grade serious carcinoma. The speaker further discusses the micropapillary variant and microinvasion in serious borderline tumors. They also explore the concept of implants in serious tumors and explain the difference between non-invasive implants and invasive implants, which are classified as low-grade serious carcinoma. Additionally, the speaker mentions the role of immunohistochemistry in diagnosing and characterizing serious tumors, including the use of markers such as WT1, P53, and ER/PR. The speaker also briefly discusses the pathogenesis of serious ovarian carcinomas and highlights the importance of the fallopian tube as the site of origin for many of these tumors. They explain how molecular markers such as P53 and HRD status can help guide treatment decisions. Finally, the speaker mentions the use of neoadjuvant therapy in ovarian cancer treatment and the importance of accurately diagnosing the primary site of origin in these cases.
Asset Subtitle
Radhika Srinivasan
September 2023
Keywords
serious tumors
borderline tumors
low-grade proliferative tumors
histological characteristics
stromal invasion
immunohistochemistry
molecular markers
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