Endometrial Cancer Tumor Board: Matching the right therapy to the right patient-Endometrial Cancer Tumor Board: Matching the right therapy to the right patient

Video Transcription

Video Summary

In this video, Wendell Bowman introduces the IGCS 360 initiative aimed at providing education on personalized therapy for cancer patients. The video features two experts discussing challenging cases of endometrial cancer. The first case involves a 64-year-old woman with stage 3C2 endometrial carcinoma. The audience participates in choosing routine evaluations and surgical approaches for this case, with MRI and minimally invasive hysterectomy with sentinel nodes being the preferred choices. The case progresses with nodal involvement and the discussion of treatment options for a stage 3C2 endometrial carcinoma. The majority selects chemotherapy plus pelvic and periodic radiation. The case further progresses with lung recurrence, and the audience selects pembrolizumab plus lenvatinib as the treatment option.<br /><br />Dr. Ramez Eskander discusses the current treatment options for endometrial cancer, including chemotherapy, hormonal therapy, immune checkpoint inhibitors, anti-HER2 agents, and targeted therapy. He emphasizes the significance of molecular subtyping in guiding treatment decisions. The ongoing and future clinical trials in improving treatment outcomes for endometrial cancer patients are also highlighted.<br /><br />Another case discussed in the video involves a patient with clear cell carcinoma in the endometrium. The treatment options for various stages of recurrence are presented, including chemotherapy, brachytherapy, radiation, immunotherapy, and surgical resection. The importance of further research in determining the best treatment strategies for clear cell carcinoma is emphasized.<br /><br />Overall, the video provides valuable insights into the treatment options for endometrial cancer patients and highlights the importance of personalized therapy based on individual characteristics and disease stage.

Keywords

IGCS 360 initiative

education

personalized therapy

cancer patients

endometrial cancer

challenging cases

64-year-old woman

stage 3C2 endometrial carcinoma

treatment options

chemotherapy

molecular subtyping