In The Know-October 2020

October 2020

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This document contains a compilation of abstracts related to the field of gynecologic oncology from the journal Gynecologic Oncology. The abstracts cover a range of topics including the impact of the bivalent HPV vaccine on HPV infections, the durability of the vaccine's effectiveness, and the molecular classification of high-risk endometrial cancer. <br /><br />One study evaluated the durability of the bivalent HPV vaccine and found that cross-protection against certain HPV types remained strong even after 11 years post-vaccination. The study also showed that the vaccine provided significant protection against HPV-related cancers. Another study investigated the efficacy of different schedules of the bivalent HPV vaccine and found that even a single dose of the vaccine provided substantial cross-protection against HPV infections.<br /><br />In a separate study, the molecular classification of high-risk endometrial cancer was evaluated, and it was found that different molecular subgroups had varying prognoses and responses to adjuvant therapy. The study concluded that molecular classification should be incorporated into the risk stratification of patients with high-risk endometrial cancer.<br /><br />Other abstracts in the document discuss topics such as the impact of molecular factors on T-cell inhibition in ovarian cancer ascites, the cost-effectiveness of genomic screening for hereditary breast and ovarian cancer, and the development and validation of gene expression predictors for high-grade serous ovarian carcinoma.<br /><br />Overall, the abstracts provide a snapshot of the latest research in gynecologic oncology, highlighting important findings in areas such as HPV vaccination, molecular classification, and personalized treatment approaches.

Keywords

gynecologic oncology

bivalent HPV vaccine

HPV infections

molecular classification

high-risk endometrial cancer

cross-protection

adjuvant therapy

T-cell inhibition

genomic screening

personalized treatment approaches