In The Know-October 2023

October 2023
Pdf Summary
Ed's List, titled "Gyn Onc Literature of Significance," is a compilation of recent research and studies in the field of gynecologic oncology. The list includes summaries of the following studies:<br /><br />1. Gyn ONC Garage: This video review discusses the long-term postoperative outcomes for patients undergoing common surgeries and the impact of surgeon sex on these outcomes.<br />2. Patient Satisfaction: A study found that women physicians received lower patient satisfaction scores in outpatient gynecology care.<br />3. Salpingectomy and Ovarian Cancer Risk: A study investigated the risk of ovarian cancer after salpingectomy in Ontario and found a link between the two.<br />4. Tisotumab Vedotin in Cervical Cancer: The innovaTV 301 study evaluated the use of tisotumab vedotin in the treatment of recurrent or metastatic cervical cancer, showing improved overall survival, progression-free survival, and objective response rate.<br />5. Plasma DNA Methylation Analysis for Ovarian Cancer Detection: An analysis of samples from a case-control study and an ovarian cancer screening trial examined the use of cell-free DNA methylation analysis for the detection of ovarian cancer.<br />6. Universal Testing in Endometrial Cancer: A study assessed the implementation of next-generation sequencing for the detection of microsatellite instability and its impact on endometrial cancer management.<br />7. Pelvic Inflammatory Disease and Ovarian Cancer Risk: A case-control study in Sweden explored the association between pelvic inflammatory disease and the risk of epithelial ovarian cancer.<br />8. BRCA1-BARD1 E3 Ligase Activity in DNA Repair: A study investigated the role of BRCA1-BARD1 E3 ligase activity in homology-directed DNA repair.<br />9. Discordant MMR/MSI Testing in Endometrial Cancer: Researchers examined the discordance between mismatch repair and microsatellite instability testing in endometrial cancer and its clinical implications.<br />10. Mirvetuximab Soravtansine-Gynx for Ovarian Cancer: The FDA approved mirvetuximab soravtansine-gynx for the treatment of FRα-positive, platinum-resistant ovarian cancer.<br />11. OvaPrint Liquid Biopsy for Ovarian Cancer Risk Assessment: A liquid biopsy test called OvaPrint was developed for the risk assessment of high-grade serous ovarian cancer.<br />12. Prognostic Impact of Cytoreductive Surgery in Ovarian Cancer: A study compared the outcomes of primary cytoreductive surgery and cytoreductive surgery after neoadjuvant chemotherapy in advanced epithelial ovarian cancers.<br />13. Hyperthermic Intraperitoneal Chemotherapy for Ovarian Cancer: Long-term findings from the OVHIPEC-1 trial on the use of hyperthermic intraperitoneal chemotherapy in ovarian cancer were reported.<br />14. Reducing Unnecessary Oophorectomies in Pediatric Patients: A study evaluated a preoperative risk stratification algorithm to decrease unnecessary oophorectomies for benign ovarian neoplasms in pediatric patients.<br />15. Tables of Contents for Gynecologic Oncology: A link is provided to the tables of contents for recent issues of the journal Gynecologic Oncology.<br /><br />Overall, Ed's List provides a summary of the key findings and implications of these studies in the field of gynecologic oncology.
Keywords
Gynecologic Oncology
Long-term postoperative outcomes
Patient satisfaction
Salpingectomy
Tisotumab Vedotin
Ovarian cancer detection
Universal Testing
BRCA1-BARD1 E3 Ligase Activity
Mirvetuximab Soravtansine-Gynx
Hyperthermic Intraperitoneal Chemotherapy