Pragmatic Clinical Trial Resources-Challenges Across Borders - What you need to do before you start developing your trial

Challenges Across Borders - What you need to do before you start developing your trial

Video Transcription

Video Summary

The webinar, hosted by IGCS and GCIG, introduced an opportunity for early career researchers to submit pragmatic trial ideas for possible funding and presentation in Montreal. Mary Aiken explained that pragmatic trials aim to reflect real-world care through inclusive populations and streamlined protocols. John Andrews then outlined key steps for designing successful global pragmatic trials: confirm regional standards of care, ensure broad patient representativeness, minimize patient and site burden, involve patient advocates early, and keep outcomes clinically meaningful and easy to collect. He emphasized the need for clear ethics, consent, translation, data transfer, governance, and budgeting plans across countries. In the Q&A, he stressed that pragmatic trials should be inclusive, feasible in routine care, and valuable for low- and middle-income settings. He cited SHAPE and LACC as examples. The session closed with encouragement to prepare for a June 25 FAQ webinar and upcoming Montreal workshop.

Asset Subtitle

Presented by John Andrews
Recorded on June 4, 2026

Keywords

pragmatic trials

global clinical research

early career researchers

trial design

inclusive patient populations

Montreal workshop