Recurrence Endometrial cancer with squamous differentiation-Recording

Video Transcription

Video Summary

In this video, Dr. Sakiti presents a case of recurrent endometrial cancer. The patient is a 52-year-old woman who initially presented with heavy vaginal bleeding and was diagnosed with endometrioid endometrial carcinoma with squamous differentiation. She underwent surgery and received adjuvant treatment including external beam radiation therapy. However, she later presented with abdominal pain and bloating, and a CT scan revealed nodal recurrence and an abdominal wall hernia. She is currently on palliative care and discussions regarding chemotherapy and other treatment options are ongoing. The panel discusses the case and considers the role of adjuvant therapy, molecular profiling, neoadjuvant chemotherapy, and the use of stereotactic radiotherapy for recurrent disease. The consensus is that treatment decisions should be individualized based on the patient's specific circumstances, risk factors, and available resources. The use of poly in predictive molecular profiling is also discussed, with the understanding that further research and evidence are needed to fully understand its impact on treatment decisions. Overall, the panel emphasizes the need to provide the best possible care for each patient, taking into account available treatment options, patient response to therapy, and quality of life considerations.

Keywords

recurrent endometrial cancer

endometrioid endometrial carcinoma

adjuvant treatment

abdominal pain

nodal recurrence

palliative care

molecular profiling

chemotherapy

treatment options