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Personalized Management of Advanced or Recurrent Endometrial Cancers: Navigating pMMR, dMMR Subtypes, or Molecular Classifications
Description

IGCS and Eisai welcomes you to view Personalized Management of Advanced or Recurrent Endometrial Cancers: Navigating pMMR, dMMR Subtypes, or Molecular Classifications Industry Supported Symposium presented at the IGCS 2024 Annual Global Meeting in Dublin, Ireland.  This course offers an in-depth exploration of personalized treatment approaches for endometrial cancers, focusing on proficient mismatch repair (pMMR), deficient mismatch repair (dMMR) diseases and molecular classification in the recurrent setting. Through case-based studies, and analysis of clinical data, participants will gain insights into tailored treatment strategies, including the use of immune checkpoint inhibitors, chemotherapy, and targeted therapies. The course also examines the challenges of managing treatment toxicities and poor tolerance in pMMR patients, utilizing evidence from post-adjuvant sub-analyses to inform decision making and optimize patient outcomes. 

Presentation: pMMR vs dMMR Disease, Molecular Considerations in the Recurrent and First Line Setting
Presenter: John Chan, MD, California Pacific Medical Center, Sutter Health, USA

Dr. John K. Chan is the Division Director of Gynecologic Oncology and the Denise & Prentis Cobb Hale Endowed Chair at the California Pacific Medical Center and serves as a Principal Investigator Lead of the Sutter Cancer Research Consortium. He is an Adjunct Clinical Professor at University of California San Francisco, Stanford University and Dartmouth School of Medicine. Dr. Chan earned his medical degree at University of California, Los Angeles and completed his Fex Rutledge fellowship at MD Anderson Cancer Center and gynecologic oncology fellowship at University of California Irvine. He has conducted numerous gynecologic cancer clinical trials and has received grants and awards, including those from the National Cancer Institute, the Ovarian Cancer Research Foundation, Gynecologic Cancer Foundation, and the Gynecologic Oncology Group. Dr. Chan has authored and co-authored over 220 peer-reviewed journals including New England Journal of Medicine, Journal of the American Medical Association, Lancet Oncology, Journal of Clinical Oncology, Gynecologic Oncology and International Journal of Gynecologic Cancers. He is also the co-author of five textbooks in the field of Gynecologic Oncology. Academically, he has received numerous outstanding medical student and resident teaching awards from Stanford University and University of California School of Medicine at Irvine and San Francisco. Clinically, he is consistently selected as the Best Doctor Award as recognized by the U.S. News and World Report, Castle Connolly Medical Ltd, and San Francisco Magazine. 

Save the date for the next two presentation releases! 
June 2025 - Therapeutic Strategies for dMMR/pMMR Endometrial Cancers: Insights from Case Based Analysis (2nd line metastatic)
September 2025 - Treatment Sequencing in pMMR Endometrial Cancers: Insights from Adjuvant to Targeted Therapies (1st line metastatic) 

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Supported in part by


Eisai have sponsored this initiative with IGCS and had no input into or influence over the content.
Summary
Availability: On-Demand
Cost: FREE
Recommended
Contact education@igcs.org for assistance.
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