Didactics-Controlled clinical trials

Video Transcription

Video Summary

In this video, Florencia Noll, a gynecologist-oncologist from Argentina, discusses controlled clinical trials. She explains that there are two types of research studies: observational and interventional/experimental. Observational studies aim to observe and collect data without influencing the participants, while interventional studies involve deliberately influencing the course of events to investigate the effects of an intervention. Noll focuses on randomized controlled trials (RCTs), which are considered the gold standard in evidence-based medicine. RCTs involve randomly assigning patients to control and treatment groups and aim to establish the superiority, equivalence, or non-inferiority of the intervention. Noll explains the different types of RCTs based on the specific hypotheses being tested. She also discusses various aspects of the RCT process, including patient recruitment, randomization strategies, blinding, outcome selection, analysis plans, and reporting guidelines. Noll concludes by highlighting the advantages and challenges of conducting clinical trials and emphasizes the importance of teamwork and mentorship in the process.

Asset Subtitle

Florencia Noll

Keywords

Florencia Noll

gynecologist-oncologist

controlled clinical trials

observational studies

interventional studies