Didactics-Endometrial Cancer Case

Video Transcription

Video Summary

In this video, a physician discusses a case presentation of a 72-year-old postmenopausal female who presented with postmenopausal spotting. The patient had a history of obesity, type 2 diabetes, and hypertension. The physician conducted a thorough evaluation of the patient's family history and symptoms and discovered that she had intermittent abdominal pain, changes in appetite, and mild constipation. The patient had previously undergone an endometrial biopsy and was diagnosed with adenocarcinoma. However, as the clinical picture did not fully match the diagnosis, further workup was performed, revealing thickened endometrium and omentum, as well as an elevated CA-125 level. The patient underwent surgery, which involved the removal of the uterus, adnexa, omentum, and peritoneal stripping. The final diagnosis was advanced stage uterine serous carcinoma. The physician goes on to discuss the different types and subtypes of endometrial cancer, as well as the risk factors, symptoms, and treatment options for serous carcinoma. The importance of surgical staging, optimal cytoreduction, and the use of chemotherapy, radiotherapy, and targeted therapies are also highlighted. The physician emphasizes the need for ongoing research and the exploration of new treatment options for patients with recurrent or advanced disease.

Asset Subtitle

Siobhan Kehoe
March 2023

Keywords

postmenopausal spotting

adenocarcinoma

advanced stage uterine serous carcinoma

surgical staging

chemotherapy

targeted therapies