Didactics-Genetic testing and counselling in gynecological malignancies

Genetic testing and counselling in gynecological malignancies

Video Transcription

Video Summary

The video discusses the rise in cancer cases over the next 20 years and the challenges faced by clinicians and professionals in the field. It highlights the limitations of using family history for cancer diagnosis and promotes the use of unselected gene testing. The video emphasizes the need for context-specific pathways and models for implementing gene testing at cancer diagnosis, as the current models are based on largely Western datasets and may not perform as well in non-Western populations. The benefits of gene testing include better identification of high-risk groups, prevention and risk management, improved prognostication opportunities for novel treatments, and access to clinical trials. The video also discusses the genes recommended for testing in ovarian and endometrial cancer, as well as the advantages and limitations of gene testing. It concludes by suggesting the implementation of mainstream gene testing at cancer diagnosis and the potential benefits of molecular classification.

Asset Subtitle

Ranjit Manchanda
March 2023

Keywords

cancer cases

gene testing

context-specific pathways

high-risk groups

clinical trials

molecular classification