Didactics-Management of Gestational Trophoblastic Disease (Nepal ECHO)

Management of Gestational Trophoblastic Disease (Nepal ECHO)

Video Transcription

Video Summary

The video discusses the management of gestational trophoblastic disease (GTD). It covers various aspects including epidemiology, clinical presentation, investigations, phagostaging, management, and follow-up. The prevalence of GTD is discussed, with hydratiform mole being the most common type, followed by invasive mole and choriocarcinoma. The video also mentions a study on GTD patients, highlighting the different histological types observed. Clinical presentations of GTD include abnormal vaginal bleeding and symptoms related to metastasis in organs such as the liver, lungs, brain, and intestines. Prognosis for GTD is generally good, with a high cure rate and the ability to preserve fertility. Investigations involve history taking, physical examination, blood tests, and imaging studies. The phagostaging criteria for GTD are explained, along with the WHO scoring system for prognostication. Management options include single agent chemotherapy, prophylactic chemotherapy, and multi-agent chemotherapy depending on the risk. The role of surgery, radiotherapy, and follow-up are also discussed.

Asset Subtitle

Bishal Paudel
September 2023

Keywords

gestational trophoblastic disease

clinical presentation

investigations

management

follow-up