Didactics-VAIN Management

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Video Summary

The presentation reviews the management of vaginal intraepithelial neoplasia (VAIN), based on the European Society of Gynecological Oncology and related societies' 2023 consensus statement. VAIN is a rare and underdiagnosed condition that can progress to invasive cancer, often related to HPV. Diagnosis relies on colposcopy and biopsy, with VAIN being multifocal and often asymptomatic. The talk emphasizes the necessity of considering patient characteristics and lesion specifics for treatment. Management options range from conservative treatments like local excision and laser ablation to medical therapies such as Imiquimod. Vaginal cancer can develop following treatments like hysterectomy if underlying HPV infection persists. Follow-up is crucial, with long-term monitoring recommended due to the disease's potential to recur or progress. Advances in diagnostic and therapeutic techniques aim to improve outcomes in VAIN management, ensuring proper differentiation between benign, pre-malignant, and malignant lesions.

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Natacha Phoolcharoen
March 2025

Keywords

Vaginal Intraepithelial Neoplasia

HPV

Colposcopy

Imiquimod

Laser Ablation

European Society of Gynecological Oncology